Radiance Beauty & Day Spa is delighted to introduce to the Irish market the innovative ground-breaking cosmeceutical CALECIM® Professional which has been derived from over a decade of research in globally recognized stem cell technology.

This is a product that is a breakthrough in Stem Cell Technology and patented in 41 territories. All CALECIM® Professional skin care products are enhanced with a patented protein mix derived from umbilical cord lining stem cells, known as CALECIM® Rejuvenating Conditioned Media.

CALECIM® is a powerful source of youth-activating proteins and growth factors, with fast-acting, anti-aging benefits for skin, delivered through scientifically proven inter-cellular signalling technology.

Treatment with CALECIM® results in improved appearance of fine lines, wrinkles, firmness and decreased laxity within the first 14 days of use (with optimal results in 90 days). It can also be used in-clinic as a post-treatment adjunct to optimize aesthetic results and reduce procedure downtime.

– Derived from ethical source of Stem Cells derived from Umbilical Cord Lining
– Active ingredient is Rejuvenating Conditioned Media: a potent and concentrated mix of proteins and growth factors derived from stem cells
– Stimulates anti-aging biochemical pathways in skin with unique “Youth Messaging” system.


CALECIM® Professional is a wholly owned subsidiary of CellResearchCorp, a biotechnology company that owns the patented technology for scientifically derived stem cells from cord lining tissue.

Over 10 years ago, our scientists discovered that the umbilical cord lining tissue holds the richest source of stem cells from a non-embryonic source. The active ingredient of CALECIM® Professional, a potent protein mix derived from cord lining stem cells, which is produced in ISO-certified laboratories.


Stem cell therapy has been the domain of medical applications and research until now. Since the discovery of a new, potent and plentiful source of stem cells in the umbilical cord lining, CellResearchCorp has brought real stem cell technology to the cosmeceutical world for the first time, to be utilized for the maintenance of skin health.

Stem cells have great potential for all kinds of therapies because of their remarkable potential to develop into many different cell types in the body, especially during early life and growth. There are different types of stem cells, of which two are found in the umbilical cord lining: Mesenchymal Stem cells, which differentiate into inner organs including the dermal layer of the skin; and Epithelial Stem Cells, which differentiate into the epidermal layer.
The protein mix derived from these two types of stem cells are able to effectively communicate with every layer of the skin to rejuvenate and renew.

This is what makes the active ingredient of CALECIM® Professional so unique.


Stem cells relay their repair and renew messages through proteins that they excrete. CALECIM® Professional’s active ingredient, Rejuvenating Conditioned Media, is a collection of these messages.

This unique “Youth Messaging” technology directs skin to Increase Glycoprotein production (such as Hyaluronic Acid) to increase skin fullness, mobilize skin cells, so that they are encouraged to move in a specific direction, especially when there are wounds or traumas that need to be healed. It also activates skin cells to divide or instruct senescent cells to die, to restore epidermal cell turnover CALECIM® Professional Rejuvenating Conditioned Media.


In-vitro Tests show that exposure to Cord Lining Conditioned Media result in

  • Increased epidermal proliferation and cell turnover
  • Improved dermal density (skin thickness) with production of glycosaminoglycans
    and increased collagen synthesis


1 x Treatment: £175.

A Course of 3 for £450.